Relationship of patent ductus arteriosus management with neonatal AKI.

April 19, 2021

  • Guillet R, Selewski DT, Griffin R, Rastogi S, Askenazi DJ, D'Angio CT; Neonatal Kidney Collaborative. Journal of Perinatology volume 41, pages 14411447 (2021)
  • Of 526 neonates with sufficient data to diagnose AKI, 157 (30%) had PDA (61 conservative management, 62 pharmacologic treatment only, 34 surgical ligation). In analyses adjusted for sex, birthweight, gestational age, caffeine, nephrotoxin exposure, vasopressor and mechanical ventilation use, with conservative management as reference, there were no differences among treatment cohorts in the odds of AKI.
  • doi: 10.1038/s41372-021-01054-1